Pulse oximetrr2/25/2023 ![]() Oximetry measurements within Intensive Care Units (ICUs) were not included in this study. Pulse oximetry measurements with a paired blood gas measurement of oxygen saturations within a 30-minute time window were used as the primary outcome. Oxygen saturations are recorded electronically. The study used routinely collected electronic data for patients admitted to Nottingham University Hospitals NHS trust between 1 February 2020 and 31 December 2021 with either a clinical or a microbiological diagnosis of SARS-CoV-2 infection. We have explored the association between smoking status and measurement error for pulse oximetry measurements of oxygen saturation. To date, no robust real-world clinical data on acutely unwell patients exist to clarify the impact of smoking status and blood carboxyhaemoglobin levels of the measurement error of oxygen saturation by pulse oximeters. ![]() This was reported in a series of 16 patients with carbon monoxide poisoning from 1994 which resulted in higher pulse oximetry measurements than the true values, with the comment that this phenomenon may also extend to oxygen saturation measured in smokers as well. One group would be tobacco smokers, as the inhaled carbon monoxide modifies the haemoglobin molecule within 1–2 min of inhaling tobacco smoke, and the subsequent increase in blood carboxyhaemoglobin levels modifies the pulse oximetry signal. ![]() ![]() Pulse oximeters provide a non-invasive measurement of oxygen saturation and are now routinely used to assess patients, inform medical decision making and monitor subsequent clinical status.Īs pulse oximeters are now so widely used, it is important to identify any patient groups in whom they may also have a systematic bias that may impair the delivery of medical care to these individuals. ![]()
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